Evaluation of Long-Term Inflammatory Responses after Implantation of a Novel Fully Bioabsorbable Scaffold Composed of Poly-L-lactic Acid and Amorphous Calcium Phosphate Nanoparticles

Table 5

Immunohistochemistry results.

	1 month	6 months	12 months	24 months
MMP-9 positive index
PLLA	8.65 ± 2.65	13.04 ± 4.77	21.13 ± 4.89	29.32 ± 5.89
PLLA/ACP	7.43 ± 2.71	6.94 ± 3.30	9.58 ± 5.58	8.49 ± 4.23
values	0.18	0.00	0.00	0.00
NF-κB positive index
PLLA	29.38 ± 3.96	34.44 ± 4.07	40.00 ± 3.19	50.62 ± 5.12
PLLA/ACP	26.51 ± 5.15	30.91 ± 3.42	26.24 ± 4.52	20.29 ± 5.39
values	0.07	0.02	0.00	0.00

Notes: Data are presented as mean ± standard deviation. values: the PLLA/ACP group compared with the PLLA group.