Evaluation of the Genotoxic and Antigenotoxic Effects of Andiroba (Carapa guianensis Aublet) Oil and Nanoemulsion on Swiss Mice

Table 3

Frequency of micronuclei in polychromatic erythrocytes (MNEPC) and normochromatic (MNPCE) in bone marrow of Swiss mice after 14 treatments with AO, AN, and DOX and their respective controls.

	AO control	AN control	AO (2000 mg/Kg)	AN (2000 mg/Kg)	AO (2000 mg/Kg) + DOX	AN (2000 mg/Kg) + DOX	DOX
	G1	G2	G3	G4	G5	G6	G7
MNEPC	0.07 (±0,03)	0.05 (±0.04)	0.07 (±0.06)	0.10 (±0.05)	0.22 (±0.14)	0.77 (±0.26)	1.37 (±0.70)
Reduction (%)	-	-	-	-	89	62	-
MNENC	0.07 (±0.06)	0.07 (±0.049)	0.04 (±0.03)	0.05 (±0.04)	0.17 (±0.16)	0.22 (±0.16)	0.34 (±0.10)
Reduction (%)	-	-	-	-	45	42	-

Note. Nonparametric Kruskal-Wallis test; Dunn’s multiple comparisons test. Differs statistically compared to G1. Differs statistically compared to G2. Differs statistically compared to G3. Differs statistically compared to G4.