Preparation and Drug Release Study of Novel Nanopharmaceuticals with Polysorbate 80 Surface Adsorption

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Coverage</td><td class="align_center"><i>K</i><sub>A</sub> (10<sup>5</sup>/M)</td><td class="align_center">△<i>H</i> (cal/mol)</td><td class="align_center">△<i>S</i> (cal/mol/deg)</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">2.70 ± 0.372</td><td class="align_center">2.98 ± 1.66</td><td class="align_center">1710 ± 311.4</td><td class="align_center">30.8</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Affinities (<i>K</i><sub>A</sub>), degree of coverage, and enthalpy changes upon binding when polysorbate 80 was titrated into nanoparticle solution at 25°C.</div>

Journal of Nanomaterials

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Table 2

Table 2: Preparation and Drug Release Study of Novel Nanopharmaceuticals with Polysorbate 80 Surface Adsorption 