Preparation and Drug Release Study of Novel Nanopharmaceuticals with Polysorbate 80 Surface Adsorption

Table 3

Particle size, polydispersity index (PDI), zeta potential, drug loading, and entrapment efficiency of the three kinds of CHP NPs.

NPs	Particle size (nm)	PDI	Zeta potential (mV)	Drug loading (%)	Entrapment efficiency (%)
CHP	257.5 ± 3.05	0.169 ± 0.02	−2.81 ± 0.27	—	—
DZP-CHP	266.3 ± 4.46	0.122 ± 0.01	−0.66 ± 0.04	14.78 ± 1.19	88.77 ± 2.60
PS-DZP-CHP	335.2 ± 5.46	0.138 ± 0.03	−2.22 ± 0.86	8.25 ± 1.80	91.28 ± 4.57