Review Article
Exosomes: A Paradigm in Drug Development against Cancer and Infectious Diseases
Table 5
Novel strategies/devices of exosomal removal for cancer and infectious disease therapy.
| Mechanism of exosomal removal | Disease | Effect | Ref. |
| Extracorporeal hemofiltration of exosomes | Hepatitis C | Minimize viral titers in patients | [39] |
| Exosome enervation by Dimethyl amiloride (DMA) in mice | Colorectal cancer | Restore the cyclophosphamide (CTX) anti-tumor effect through the inhibition of MDSC functions | [40] |
| Extracorporeal filtration of exosomes (The Hemopurifier) | Advanced stage of cancer patients | To remove exosomes from the blood | [41] |
| Adjunct therapeutic method HER2osome | Breast cancer | Decrease the tumor secreted HER2 containing exosomes in circulation and afterward impede HER2 positive breast cancer progression | [42] |
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