Exosomes: A Paradigm in Drug Development against Cancer and Infectious Diseases

Table 6

Exosomes used for infectious diseases treatment.

Exosomal cargo	Secreting cell	Biological activity	Ref.
Exosomes pulsed with Toxoplasma gondii antigens	Dendritic cells	A defensive immune response against Toxoplasma gondii infection	[43, 44]
Exosomes pulsed with Leishmania major antigens	Dendritic cells	A defensive immune response against L. major infection	[45]
Exosomes containing M. tuberculosis antigens	Macrophage infected with M. Tuberculosis	Tuberculosis vaccine, activate innate/acquired immune responses	[46]
shRNA against HCV replication-loaded exosomes	Transfected into several cell types	Decrease in HCV infection of liver cells	[47]