Controlled Release of Ursodeoxycholic Acid from Pullulan Acetate Nanoparticles to Modulate Glutamate-Induced Excitotoxicity in PC-12 Cells

Figure 7

Standard images were captured with fluorescence microscope. Changes of caspase-3 expression in PC-12 cells challenged with or without glutamate and subsequently incubated with or without UPN (1 or 5 μg/mL) were evaluated by immunofluorescence study using anti-caspase-3 antibody (green). DAPI was used for nuclear staining (blue). Abbreviations used: Con, untreated control; UPN, UDCA-PA nanospheres.