Journal of Nanomaterials / 2019 / Article / Fig 2

Research Article

Nanocrystalline Hydroxyapatite-Based Scaffold Adsorbs and Gives Sustained Release of Osteoinductive Growth Factor and Facilitates Bone Regeneration in Mice Ectopic Model

Figure 2

NHA incorporated with rhBMP2 enhanced osteogenic differentiation of C2C12 cells in vitro. (a) Cell proliferation and (b) ALP activity. Gene expression of (c) Alp, (d) Runx2, (e) Col1α1, and (f) Osterix in C2C12 cells at day 7. Data are presented as the mean ± SD, . Significant effect of the treatment, and . Alp: alkaline phosphatase, Runx2: Runt-Related Transcription Factor 2, Col1α1: collagen 1 alpha 1.

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