Titanium Dioxide Nanoparticles Induce Mitochondrial Dynamic Imbalance and Damage in HT22 Cells

Figure 3

STED super-resolution microscopy revealed submitochondrial structures. (a) Confocal microscopy of mitochondria in control, 0.8 μg/mL, and 20 μg/mL groups. (b) STED super-resolution microscopy revealed submitochondrial structures of the same region using confocal microscopy. (c) Enlarged views of the white boxes in (b). (d–f) Averaged intensity distribution along the mitochondrial tubule sections in the corresponding red boxes in (c). Scale bars: 5 μm in (a) and (b); 1 μm in (c).