Research Article

Optimization of Synthesis Parameters of Mesoporous Silica Nanoparticles Based on Ionic Liquid by Experimental Design and Its Application as a Drug Delivery Agent

Table 2

Independent variable of BBD with experimental and predicted results.

RunFactor, Response,
(g) (g) (°C) (m2 g−1) (nm)

10.500.1340999.05128.509
21.000.1340900.74328.561
30.750.0640963.30735.769
40.750.2040900.97929.126
50.500.0665851.02539.189
61.000.0665790.19738.563
70.500.2065879.38531.153
81.000.2065572.76929.859
90.750.1365842.82332.234
100.500.1390707.36941.457
111.000.1390541.02337.409
120.750.0690509.54852.292
130.750.2090705.05433.373

: mass of IL; : mass of TEA; : temperature; : SA; : PS.