Optimization of Synthesis Parameters of Mesoporous Silica Nanoparticles Based on Ionic Liquid by Experimental Design and Its Application as a Drug Delivery Agent
Table 2
Independent variable of BBD with experimental and predicted results.
Run
Factor,
Response,
(g)
(g)
(°C)
(m2 g−1)
(nm)
1
0.50
0.13
40
999.051
28.509
2
1.00
0.13
40
900.743
28.561
3
0.75
0.06
40
963.307
35.769
4
0.75
0.20
40
900.979
29.126
5
0.50
0.06
65
851.025
39.189
6
1.00
0.06
65
790.197
38.563
7
0.50
0.20
65
879.385
31.153
8
1.00
0.20
65
572.769
29.859
9
0.75
0.13
65
842.823
32.234
10
0.50
0.13
90
707.369
41.457
11
1.00
0.13
90
541.023
37.409
12
0.75
0.06
90
509.548
52.292
13
0.75
0.20
90
705.054
33.373
: mass of IL; : mass of TEA; : temperature; : SA; : PS.