Hydroxyapatite Nanoparticle Coating on Polymer for Constructing Effective Biointeractive Interfaces

Figure 12

(a) Scheme of the evaluation of the effect on the interfacial phenomenon during the initial adhesion between the proteins and the osteoblast-like cells by QCM-D and the confocal laser scanning microscope (CLSM). CLSM images of the cells adhered on (b) fetal bovine serum (FBS), (c) FBS-Fgn, (d) FBS-Ab, and (e) FBS-collagen adsorbed on the HAp. Reprinted with permission from [252], M. Tagaya et al. Langmuir, 27, 7645—7653 (2011), © 2011, American Chemical Society.