Research Article

Development of Innovative Polymer-Based Matricial Nanostructures for Ritonavir Oral Administration

Table 1

Composition of nanoparticles (EUD = Eudragit® RS100, PCLT = polycaprolactone triol, and RIT = ritonavir).

NPR-300NPR-900

Aqueous phase
Polysorbate 80 (mg)7676
Water (mL)5454
Organic phase
EUD (mg)100100
PCLT 300 (mg)330
PCLT 900 (mg)330
Acetone (mL)2727
RIT (mg)1010