In Vitro Safety Evaluation and In Vivo Imaging Studies of Superparamagnetic Iron Oxide Nanoparticles through Biomimetic Modification

Figure 6

C(RGDyK)-PDA-SPION contrast agent tumor-bearing mice with -weighted image. The -weighted image changes of C(RGDyK)-PDA-SPION on the liver tissue and the tumor tissue of the tumor-bearing mice (ellipse labeled as liver, circle labeled as tumor). Two hours is probably the best imaging time of C(RGDyK)-PDA-SPION in the tumor, which was about one hour later than the optimal liver imaging time.