3D Nanostructures for Tissue Engineering, Cancer Therapy, and Gene Delivery

Table 1

GO-based nanoparticle application in the engineering of bone tissue.

Method of NP synthesis	Cell type	Mechanical strength (MPa)	Application	Ref.
Modified Hummers’ method	mMSCs	53	In vivo	[48]
Modified “Hummers’ and Offeman’s” method	Osteogenesis of MC3T3-E1 preosteoblasts	—	In vivo	[49]
Modified Hummers’ method	MC3T3 cells	10.0	In vitro	[50]
Modified Hummers’ method	Rat mesenchymal stem cell line		In vivo and in vitro	[51]
Modified Hummers’ method	Mesenchymal stem cells		N/A	[51]
Electrostatic LBL assembly followed by electrochemical deposition	MC3T3-E1 osteoblast		N/A	[52]
Prepared by chemical oxidation of graphite flakes following a modified Hummers’ process	Human osteoblast cell line Saos-2		N/A	[53]
Modified Hummers’ and Offeman’s method	Osteoblastic MC3T3 E1 cell	0.125	In vitro and in vivo	[53]
Modified Hummers’ method	Human periodontal ligament stem cells	—	In vitro	[54]
Biomineralization of GO/C scaffolds	Bone marrow stromal cells	0.65	In vivo and in vitro	[55]