Preparation and Characterization of PEG-PLA Genistein Micelles Using a Modified Emulsion-Evaporation Method

Table 7

Semiquantitative PCR analysis of the mRNA levels of α-SMA and collagen I in HSC-T6 cells treated with blank lyophilized powder (BLP), genistein, or genistein lyophilized powder (GLP) for 48 h.

Gene	Concentration (μg/mL)	BLP	Genistein	GLP
α-SMA	5
	10
	20
Collagen I	5
	10
	20

Gene expression was normalized against the housekeeping gene GAPDH. Each column represents . (). ^,Significantly different at 5% and 1%, respectively, compared with 0 μg/mL; ^{#, ##}significantly different at 5% and 1%, respectively, compared with the same concentrations of BLP; ^{△, △△}significantly different at 5% and 1%, respectively, compared with the same concentrations of genistein.