Functionalization of Graphene Oxide Nanosheets Can Reduce Their Cytotoxicity to Dental Pulp Stem Cells

Figure 8

GSH level in the hDPSCs after 24 h incubation with different concentrations of graphene-based nanomaterials (25, 50, 100, 250, 500, and 1000 μg/mL). The GSH results are given in glutathione/mg protein. Results are the (bars) of three independent experiments each carried out in triplicate. There was a significant decrease in the level of GSH in the nGO group compared to the control ( value < 0.05). In contrast, cell exposure to nGO-COOH did not lead to GSH depletion, and CS-nGO had an intermediate effect. value < 0.05.