A Novel Label-Free Biosensor for Detection of HE4 in Urine Based on Localized Surface Plasmon Resonance and Protein G Directional Fixed

Table 2

Δλmax of HE4 detection in urine of different study groups with previous LSPR biosensor (based on localized surface plasmon resonance [10]).

Study groups	LSPR wavelength shift (Δλmax)					±SD; (n =5, nm)
	Case 1	Case 2	Case 3	Case 4	Cases 5
Healthy women	0.32	0.16	0.25	0.14	0.39	0.25 ± 0.11
Benign ovarian cyst patients	0.33	0.41	0.27	0.23	0.40	0.33 ± 0.08
Early ovarian cancer patients	0.42	0.12	0.58	0.29	0.33	0.35 ± 0.17