A Method for Manufacturing Flexible Microfluidic Chip Based on Soluble Material

Table 1

Manufacturing steps and parameters.

Steps	The production process	Specific methods and parameters
Step 1	Printing the ABS framework	3D printing technology is employed to fabricate the ABS framework with the size of  cm.
Step 2	Printing the HIPS mold and casting the PDMS	3D printing technology is utilized to manufacture the HIPS mold with the length of 0.8 cm and the cross-section size of .; The PDMS solution is poured with a thickness of 0.3 mm and cured at 80 degrees.
Step 3	Placing the HIPS microchannel mold	The HIPS mold is placed on the PDMS surface.; Heat curing is carried out with the temperature of 80 degrees and the time of 20 minutes.
Step 4	Casting and curing	The PDMS solution is poured with a thickness of 0.3 mm and cured at 80 degrees.
Step 5	Punching the holes	The holes with diameter of 2 mm are punched in the chip.
Step 6	Dissolving the microchannel mold in limonene solvent	The dissolving time is 30 minutes with the temperature of 100°C and the limonene concentration of 50%.
Step 7	Completing the chip	The microfluidic chip with an empty T microchannel is fabricated.