Fabrication of Agglomerated Lactose Using Fluidized Bed for Good Compressibility

Table 1

The particle characteristics of the agglomerated lactose fabricated with different lactose concentrations and sprayed volume of lactose suspension.

Lactose concentration ()	Sprayed volume (mL)	(μm)	(μm/min)	Bulk density (g/mL)	Tablet hardness (N)
5%	150	60.00	0.62	0.4708	75.21
	300	66.91		0.4948	76.55
	450	78.43		0.5032	78.22
	600	87.56		0.5229	78.76
15%	150	64.11	0.70	0.4823	76.23
	300	69.83		0.5022	77.22
	450	84.22		0.5243	78.43
	600	92.55		0.5492	80.21
25%	150	72.32	1.98	0.4874	78.34
	300	107.59		0.5121	80.54
	450	130.89		0.5317	81.28
	600	169.28		0.5618	83.45
40%	150	79.21	2.16	0.4924	85.21
	300	118.32		0.5282	87.31
	450	140.76		0.5508	87.92
	600	179.44		0.6022	88.34