Attenuation of Liver Injury via Bicyclol–Bovine Serum Albumin Nanopreparation using a Green Synthetic Approach

<div>Intracellular uptake analysis and safety evaluation of BIC-NPs: (a) the laser scanning confocal images of hepatocyte s incubated with 50 <i>μ</i>g/ml BIC-NPs for 30 min, 4 hr at 37°C, hepatocyte, stained with DAPI (blue); BIC-NPs, stained with FITC (green); (b) viability of AML-12 mouse hepatocytes cells in the presence of BIC-NPs from 1.56 to 100 <i>μ</i>g/ml for 12 hr. Data are presented as mean ± SD (<i>n</i> = 4); (c) live/dead staining of RAW264.7 cells treated with BIC or BIC-NPs (50 <i>μ</i>g/ml) for 12 hr. Red and green indicate dead and live cells, respectively.</div>

Journal of Nanomaterials

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Figure 4: Attenuation of Liver Injury via Bicyclol–Bovine Serum Albumin Nanopreparation using a Green Synthetic Approach 