Attenuation of Liver Injury via Bicyclol–Bovine Serum Albumin Nanopreparation using a Green Synthetic Approach

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Parameter</td><td class="align_center">BIC</td><td class="align_center">BIC-NPs</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left"><i>T</i><sub>max</sub> (hr)</td><td class="align_center">2 ± 1</td><td class="align_center">0.35 ± 0.22</td></tr><tr><td class="align_left"><i>C</i><sub>max</sub> (ng/ml)</td><td class="align_center">86.64 ± 13.86</td><td class="align_center">819.02 ± 287.00</td></tr><tr><td class="align_left">CL (l/h/kg)<br/>AUC<sub>0∼t</sub> (hr × ng/ml)</td><td class="align_center">3.39 ± 1.41<br/>602.83 ± 83.03</td><td class="align_center">2.95 ± 0.28<br/>1,460.56 ± 197.06</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div><i>T</i><sub>max</sub>, <i>C</i><sub>max</sub>, CL, and AUC represent the average time to reach maximum concentration, maximum concentration, the apparent total body clearance and the area under the concentration−time curve, respectively.<br/></div></td></tr></table>

<div>Pharmacokinetic parameters in blood within 24 hr after BIC and BIC-NPs administration of a single dose.</div>

Journal of Nanomaterials

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Table 2

Table 2: Attenuation of Liver Injury via Bicyclol–Bovine Serum Albumin Nanopreparation using a Green Synthetic Approach 