Milk Products Containing Bioactive Tripeptides Have an Antihypertensive Effect in Double Transgenic Rats (dTGR) Harbouring Human Renin and Human Angiotensinogen Genes

Table 2

Biochemical variables and cardiac and renal hypertrophies at the end of the three-week treatment period (mean ± SE, 𝑛=6-9).

Variable	Control	Fermented milk	Peptide	Difference between the groups, 𝑃
Urinary albumin, mg/d	22 ± 4	35 ± 8	30 ± 4	.20
PRA, ng Ang I/mL/h	90 ± 17	99 ± 30	95 ± 19	.98
BNP, pmol/L	3.1 ± 0.5	2.3 ± 0.2	3.5 ± 0.3	.24
Aldosterone, pg/mL	1228 ± 302	2551 ± 921	1494 ±218	.18
Cardiac hypertrophy index (mg/g)	5.3 ± 0	5.1 ± 0	5.1 ± 0	.59
Renal hypertrophy index (mg/g)	4.6 ± 0	4.8 ± 0	4.8 ± 0	.61