Effects of Growth Hormone and Insulin-Like Growth Factor-1 on Postoperative Muscle and Substrate Metabolism
Table 7
Glutathione concentrations and redox-status of glutathione in skeletal muscle (mmol(kg ww muscle)). Total glutathione (tGSH), reduced glutathione (GSH), oxidized glutathione (GSSG), and the redox-status of glutathione (GSH/tGSH).
D0
D3
tGSH
Control
2.02 (1.78–2.16)
1.75 (1.59–1.95)
GH
2.03 (1.97–2.43)
1.71 (1.36–1.88)*
GH-IGF-1
1.91 (1.71–1.98)
1.62 (1.40–1.79)
GSH
Control
1.67 (1.49–1.86)
1.52 (1.30–1.76)
GH
1.65 (1.52–2.16)
1.45 (1.02–1.74)*
GH-IGF-1
1.65 (1.50–1.73)
1.33 (1.25–1.47)*
GSSG
Control
0.17 (0.13–0.18)
0.13 (0.11–0.16)
GH
0.18 (0.10–0.22)
0.15 (0.07–0.17)
GH-IGF-1
0.13 (0.10–0.15)
0.15 (0.09–0.18)
GSH/tGSH
Control
0.83 (0.80–0.88)
0.86 (0.82–0.89)
GH
0.83 (0.77–0.90)
0.86 (0.75–0.91)
GH-IGF-1
0.85 (0.84–0.90)
0.83 (0.81–0.87)
*indicates a postoperative difference within the groups ( and ). are given as numbers. Values are given as median and quartiles.
