Associations of Plasma Phospholipid Omega-6 and Omega-3 Polyunsaturated Fatty Acid Levels and MRI Measures of Cardiovascular Structure and Function: The Multiethnic Study of Atherosclerosis
Table 1
Relation between baseline characteristics and plasma phospholipid DHA, LA.‡
LA quartile (n)
DHA quartile (n)
Q1
Q2
Q3
Q4
P
Q1
Q2
Q3
Q4
P
n = 324
n = 316
n = 318
n = 318
trend
n = 321
n = 318
n = 321
n = 316
trend
Age in years, mean ± SE
65.4 ± 0.7
63.7 ± 0.7
63.7 ± 0.7
62.96 ± 0.8
0.002
64.0 ± 0.9
62.7 ± 1.0
62.5 ± 1.0
62.1 ± 0.7
0.01
Gender, %female
65.5
61.1
61.3
51.8
0.0006
54.2
61.6
60
69.1
0.0008
Race/ethnicity, %
White
20.2
12.9
14.6
11.1
<.0001
24.3
15.9
4.9
5.1
0.56
Black
22.9
16.5
11.3
4.7
8.2
16.8
19.2
15.9
Chinese
12.7
19.4
24.2
34.7
4.9
18
37.2
45.8
Hispanic
44.2
51.1
49.8
49.4
62.7
49.4
38.7
33.1
BMI, mean ± SE
28.1 ± 0.3
28.4 ± 0.3
27.7 ± 5
27.7 ± 0.3
0.04
28.4 ± 0.3
28.3 ± 0.3
27.7 ± 0.3
27.5 ± 0.3
0.005
Education ≥ high school, %
82
79.5
79.7
83.9
0.51
79.9
81.1
82.8
81.1
0.64
Cigarette smoking, %
Current
15.1
16.5
20.3
18.7
0.06
21.8
17.6
17.4
11.9
0.0005
Phys activity, mod-heavy
Mean ± SE MET-h/wk
5143 ± 374
5343 ± 362
5547 ± 366
5446 ± 389
0.35
6193 ± 377
4991 ± 365
4673 ± 378
5386 ± 387
0.08
SBP, mean ± SE mmHg
128 ± 1.4
126 ± 1.3
125 ± 1.3
125 ± 1.4
0.02
127 ± 1.4
124 ± 1.3
127 ± 1.4
126 ± 1.4
0.83
Total : HDL cholesterol
4.3 ± 0.08
4.3 ± 0.08
4.2 ± 0.08
4.2 ± 0.09
0.16
4.3 ± 0.09
4.3 ± 0.08
4.2 ± 0.09
4.2 ± 0.09
0.31
Cholesterol medication, %
25.7
15
9.6
5.9
<.0001
9.1
14.4
18.9
18.2
0.001
Diabetic, %
15.5
17
15.6
15.5
0.43
15.5
17
15.6
15.6
0.86
Total energy, mean
kcal/day
1591 ± 53
1616 ± 52
1640 ± 52
1592 ± 56
0.87
1797 ± 54
1539±52
1546 ± 54
1512 ± 55
<.0001
Alcohol, avg drinks/wk
4.6
3.7
3.3
2.8
0.02
3.1
3.7
4
3.9
0.35
Saturated fat, %kcal
18.9
20.3
20.5
20.3
0.09
11.2
10.8
10.4
9.8
<.0001
Fruits, avg srv/day
1.7
1.5
1.5
1.6
0.24
1.6
1.5
1.6
1.8
0.05
Cruciferous vegetables, savg srv/day
0.35
0.37
0.4
0.37
0.35
0.33
0.37
0.38
0.44
0.002
‡Adjusted for age, gender, race/ethnicity, education, and site.
