Research Article
Distinct Effects of Calorie Restriction and Resveratrol on Diet-Induced Obesity and Fatty Liver Formation
Table 3
Incidences of the observed histopathological lesions in liver.
| | HFD | HFD + R2 | HFD + R4 | CR | LFD |
| Number of samples | 10 | 10 | 10 | 10 | 10 | Steatosis grade (degree/description) | | | | | | 3/>66% | 2 | 0 | 0 | 0 | 0 | 2/34–66% | 5 | 5 | 3 | 0 | 0 | 3/5–33% | 2 | 2 | 5 | 0 | 0 | 0/<5% | 1 | 3 | 2 | 10 | 10 |
| Lobular inflammation (degree/description) | | | | | | 2/2–4 foci/20x optical field | 1 | 0 | 0 | 0 | 0 | 1/<2 foci/20x optical field | 5 | 8 | 5 | 4 | 3 | 0/none | 4 | 2 | 5 | 6 | 7 |
| Hepatocyte ballooning (degree/description) | | | | | | 2/moderate, marked | 3 | 0 | 0 | 0 | 0 | 1/mild, few | 2 | 4 | 2 | 0 | 0 | 0/none | 5 | 6 | 8 | 10 | 10 |
| Fibrosis score (degree/description) | | | | | | 0/none | 10 | 10 | 10 | 10 | 10 |
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