Research Article

Glycemic Index and Glycemic Load and Their Association with C-Reactive Protein and Incident Type 2 Diabetes

Table 1

Baseline characteristics of 4,366 Dutch adults aged ≥55 years by tertiles of energy-adjusted glycemic index (GI).1

Low GI (<57.6)Moderate GI (57.6–<60.3)High GI (≥60.3)
( )( )( )

Age (years)67.3 (7.9)67.7 (7.7)66.9 (7.4)
Sex (% male)26.639.754.5
Body Mass Index (kg/m2)26.5 (3.6)26.2 (3.4)26.0 (3.8)
C-reactive protein (mg/L)21.6 (0.80–2.9)1.7 (0.83–3.0)1.7 (0.83–3.1)
Anti-inflammatory medication (%)8.06.67.7
Family history of diabetes (%)26.526.829.7
History of CHD (%)10.011.913.4
Smoking (% current)15.820.432.0
Education level (% low)33.633.535.7
Dietary intake
Total energy (kcal/d)1967 (555)2005 (491)1971 (464)
Carbohydrate (en%)44.2 (6.6)44.7 (6.6)43.7 (7.6)
 Mono- and disacharides (en%)24.5 (5.7)22.6 (5.5)19.7 (6.5)
 Polysacharides (en%)19.7 (3.7)22.0 (3.7)23.7 (4.4)
Energy-adjusted glycemic load119 (19.0)128 (20.1)133 (23.1)
Fiber (g/d)27.1 (8.3)26.3 (6.4)25.1 (6.6)
Protein (en%)18.0 (3.3)16.7 (2.8)16.2 (2.8)
Fat (en%)35.9 (6.3)36.5 (6.1)37.3 (6.2)
 Saturated fatty acids (en%)14.3 (3.4)14.4 (3.1)14.6 (3.1)
 Mono-unsaturated fatty acids (en%)12.3 (2.7)12.3 (2.7)12.6 (2.8)
 Poly-unsaturated fatty acids (en%)6.5 (2.8)7.0 (2.8)7.3 (2.9)
Alcohol drinkers (%)79.282.279.9
 Alcohol (g/d)2,36.0 (1.3–15.7)6.4 (1.4–16.3)8.7 (1.8–21.8)

1Means (SD) or percentages unless otherwise indicated.
2Values are expressed as median (interquartile range), because of their skewed distribution.
3Only in alcohol drinkers.