Chemopreventive Potential of Synergy1 and Soybean in Reducing Azoxymethane-Induced Aberrant Crypt Foci in Fisher 344 Male Rats

Table 3

Effect of Synergy1 and Soybean meal on incidence of aberrant crypt foci (ACF) in colon of Fisher 344 male rats.

Groups	Proximal Colon	Distal Colon	Total Colon
Control (AIN-93G)	49±9.21^a	101±11.6^a	150^a
Syn1 5%	23±1.5^b	38±4.1^b	61^b
Syn1 10%	17±4.9^bc	37±12.4^b	54^b
SM 5%	24±3.0^b	48±4.0^b	72^b
SM 10%	19±2.8^bc	44.5±6.8^b	63.5^b
Syn1 5% + SM 5%	12±5.5^bc	32±8.4^bc	42^c
Syn1 10% + SM 10%	9±2.5^c	32±4.4^bc	41^c
Syn1 5% + SM 10%	4±1.7^c	51±5.2^b	49^bc
Syn1 10% + SM 5%	7±2.4^c	27±5.2^c	34^c

Values are expressed as means ± SEM; 𝑛=3.
^abcMeans in the same column with the same letter are not significantly different by Tukey’s studentized range test (𝑃<.05).
Abbreviations used: Syn1: Synergy1 and SM: Soybean meal.