Chemopreventive Potential of Synergy1 and Soybean in Reducing Azoxymethane-Induced Aberrant Crypt Foci in Fisher 344 Male Rats

Table 4

Effect of Synergy1 and Soybean meal on total number of AOM-induced Crypts in Fisher 344 male Rats.

Groups	Proximal colon	Distal colon	Total colon
Control	141±24.89^a	310±40.53^a	444^a
Syn1 5%	53±5.1^bc	136±10.8^b	189^bc
Syn1 10%	46±10.6^bc	128±28.3^b	174^c
SM 5%	72±6.1^b	152±12.9^b	224^b
SM 10%	62±8.8^b	140±26.2^b	202^b
Syn1 5% + SM 5%	31.5±17.1^d	106±30.2^c	137.5^d
Syn1 10% + SM 10%	28±7.5^d	91±10.3^c	116^e
Syn1 5% + SM 10%	22±10.4^d	121±19.0^b	144^d
Syn1 10%+ SM 5%	27±7.1^d	72±15.0^d	99^e

Values are expressed as means ± SEM; 𝑛=3.
^abcdeMeans in the same column with the same letter are not significantly different by Tukey’s studentized range test (𝑃<.05).
Abbreviations used: Syn1: Synergy1, SM: Soybean meal.