Chemopreventive Potential of Synergy1 and Soybean in Reducing Azoxymethane-Induced Aberrant Crypt Foci in Fisher 344 Male Rats

Table 5

Effect of Synergy1 and Soybean meal on glutathione S-transferase, catalase, and superoxide-dismutase activities and reduced glutathione level in Fisher 344 male rats.

Groups	GST (μmol/mg)	GSH (mM)	CAT (μmol/mL)	SOD (μmol/mL)
Control (AIN-93G)	10.58±0.32^b	0.17±0.13^b	0.055±1.50^b	0.107±0.008^b
Syn1 5%	25.03±0.81^a	2.15±0.12^a	0.184±0.02^a	0.176±0.013^a
Syn1 10%	21.68±1.85^a	2.48±0.13^a	0.170±0.01^a	0.185±0.001^a
SM 5%	26.77±2.56^a	2.18±0.28^a	0.133±0.23^a	0.184±0.008^a
SM 10%	24.31±0.38^a	2.37±0.78^a	0.112±0.01^a	0.190±0.009^a
Syn1 5% +SM 5%	25.11±2.28^a	2.53±0.27^a	0.149±0.04^a	0.187±0.007^a
Syn1 10%+SM 10%	26.01±4.04^a	2.98±0.16^a	0.330±0.19^a	0.186±0.005^a
Syn1 5% +SM 10%	21.81±0.71^a	2.10±0.19^a	0.145±0.02^a	0.190±0.006^a
Syn1 10%+ SM 5%	25.28±1.56^a	2.13±0.09^a	0.127±0.03^a	0.186±0.003^a

Values are expressed as means ± SEM; 𝑛=3.
^abcMeans in the same column with the same letter are not significantly different by Tukey’s studentized range test (𝑃<.05).
Abbreviations used: Syn1: Synergy1, SM: Soybean meal, GST: Glutathione S-transferase, GSH: reduced glutathione, CAT: catalase, and SOD: superoxide dismutase.