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Journal of Nutrition and Metabolism
Volume 2012, Article ID 394623, 7 pages
Clinical Study

Effects of Metformin on the Regulation of Free Fatty Acids in Insulin Resistance: A Double-Blind, Placebo-Controlled Study

1Department of Internal Medicine, Center for Diabetes and Vascular Medicine, Sint Franciscus Gasthuis Rotterdam, P.O. Box 10900, 3004 BA Rotterdam, The Netherlands
2Department of Internal Medicine, Gelderse Vallei Hospital, P.O. Box 9025, 6710 HN Ede, The Netherlands

Received 17 July 2012; Revised 10 September 2012; Accepted 24 September 2012

Academic Editor: Roger A. Fielding

Copyright © 2012 Manuel Castro Cabezas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [6 citations]

The following is the list of published articles that have cited the current article.

  • Boudewijn Klop, Jan Willem F. Elte, and Manuel Castro Cabezas, “Dyslipidemia in Obesity: Mechanisms and Potential Targets,” Nutrients, vol. 5, no. 4, pp. 1218–1240, 2013. View at Publisher · View at Google Scholar
  • Hsien-Yin Liao, Mao-Feng Sun, Jaung-Geng Lin, Shih-Liang Chang, and Yu-Chen Lee, “Electroacupuncture plus metformin lowers glucose levels and facilitates insulin sensitivity by activating MAPK in steroid-induced insulin-resistant rats,” Acupuncture in Medicine, vol. 33, no. 5, pp. 388–394, 2015. View at Publisher · View at Google Scholar
  • Wenjun Zhao, Aiyun Li, Xin Feng, Ting Hou, Kang Liu, Baolin Liu, and Ning Zhang, “Metformin and resveratrol ameliorate muscle insulin resistance through preventing lipolysis and inflammation in hypoxic adipose tissue,” Cellular Signalling, vol. 28, no. 9, pp. 1401–1411, 2016. View at Publisher · View at Google Scholar
  • Rajaa El Bekay, Leticia Coín-Aragüez, Diego Fernández-García, Wilfredo Oliva-Olivera, Rosa Bernal-López, Mercedes Clemente-Postigo, Javier Delgado-Lista, Alberto Diaz-Ruiz, Rocío Guzman-Ruiz, Rafael Vázquez-Martínez, Said Lhamyani, María Mar Roca-Rodríguez, Sonia Fernandez Veledo, Joan Vendrell, María M. Malagón, and Francisco José Tinahones, “Effects of glucagon-like peptide-1 on the differentiation and metabolism of human adipocytes,” British Journal of Pharmacology, 2016. View at Publisher · View at Google Scholar
  • Nazi Aghaalikhani, Mohammad Taghi Goodarzi, Zeinab Latifi, Azam Rezaei Farimani, and Amir Fattahi, “Effects of Different Doses of Metformin on Serum Fatty Acid Composition in Type 2 Diabetic Rats,” Avicenna Journal of Medical Biochemistry, vol. 5, no. 1, pp. 22–28, 2017. View at Publisher · View at Google Scholar
  • Kunal Maniar, Amal Moideen, Amol Patil, Ankur Mittal, Amitava Chakrabarti, and Dibyajyoti Banerjee, “A story of metformin-butyrate synergism to control various pathological conditions as a consequence of gut microbiome modification: Genesis of a wonder drug?,” Pharmacological Research, vol. 117, pp. 103–128, 2017. View at Publisher · View at Google Scholar