Neonatal SSRI Exposure Programs a Hypermetabolic State in Adult Mice

Figure 2

Neonatal SSRI exposure increases adult caloric intake. Intake of standard rodent chow was recorded over a 2 week interval and compared between control mice that received 10 mL/kg/d saline (white bars) and SSRI-exposed mice that received 5 mg/kg/d sertraline (gray bars) from P1 to P14. 𝑁=27 control female (16 litters), 24 SSRI-exposed female (14 litters), 14 control male (9 litters), 12 SSRI-exposed male (10 litters); *𝑃=0.004 versus control by ANOVA.

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