Journal of Nutrition and Metabolism / 2012 / Article / Tab 5

Research Article

Blood Pressure-Lowering Mechanisms of the DASH Dietary Pattern

Table 5

Simple regression of SBP changes on changes in individual biological and vascular variables at week one.

VariableWeek one
Slope 𝑃 value

Urinary sodium0.1230.030
Urinary potassiumβˆ’0.1940.018
Urinary sodium/potassium ratio1.9870.003*
Urinary norepinephrine/creatinineβˆ’6850.197
Urinary epinephrine/creatinineβˆ’22560.376
Plasma renin activityβˆ’15.800.0003*
Plasma aldosteroneβˆ’0.4730.312
Plasma nitrite after hyperemia, %βˆ’0.3010.035*
Brachial artery flow-mediated dilation0.0210.982
Augmentation index, %0.7360.174
Pulse wave velocity, m/sβˆ’0.1840.905

*Since urinary sodium and urinary potassium are closely related with urinary sodium/potassium ratio, only urinary sodium/potassium ratio, plasma renin activity, and % change in plasma nitrite after hyperemia were further included in a multivariate regression model. All three variables remained significantly associated with SBP change at week one ( 𝑃 < 0 . 0 5 for all).

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