Associations of C-Reactive Protein to Indices of Vascular Health and the Influence of Serum 25(OH)D Status in Healthy Adults

Table 1

Descriptive statistics and outcome variables by race in young adults.

Variable	EA; (𝑁=26)	AA; (𝑁=26)	HA; (𝑁=10)	𝑃 value; ^*𝑃
Age (years)	28±9.9	32±10.5	28±5.9	𝑃=0.36
Females %	76.9%	84.6%	40%	𝑃 = 0.02
BMI (kg/m^2)	23.3±3.1	25.6±4	25.5±3.7	𝑃=0.06; ^*P = 0.03 ^a
Waist circumference (cm)	74.7±9.2	78.9±10.6	83.9±11	𝑃 = 0.05
Percent body fat (%)	29.1±6.9	34.2±8.3	31.8±8.5	𝑃=0.06; ^*P = 0.02 ^b
25(OH)D (ng/mL)	28.6±8.8	15.3±5.5	24.2±5.3	𝑃 = 0.001; ^*P = 0.001 ^c
hs-CRP (mg/L)	1.01±0.73	2.3±3.2	1.04±0.58	𝑃=0.09; ^*P = 0.05 ^d
Heart rate (beats/min)	64.9±9.2	70.1±12.3	68.4±7.3	𝑃=0.20
Brachial SBP (mm Hg)	112.3±13.8	111.2±14.3	113.8±11.2	𝑃=0.88
Brachial DBP (mm Hg)	68.4±7.9	68.8±9.1	71.3±12.5	𝑃=0.7
Aortic SBP (mm Hg)	99.6±9.6	102.9±6.9	102.9±11.8	𝑃=0.35
Aortic DBP (mm Hg)	70.4±9.4	73.7±6.7	77.1±8.5	𝑃=0.090
MAP (mm Hg)	82.4±8.7	83.7±10.1	85.3±10.5	𝑃=0.71
Aortic PP	29.2±6.7	29.3±4.7	25.8±4.9	𝑃=0.25
FMD (%)	10.6±3.9	8.8±2.8	7.8±2.2	𝑃 = 0.04; ^*P = 0.07
Aix at 75 (%)	0.74±12.1	10.9±8.6	2.2±12.3	𝑃 = 0.005; ^*P = 0.001 ^e
PWV (m/s)	6.2±0.7	7.1±1.1	6.5±0.70	𝑃 = 0.006; ^*P = 0.002 ^f

^**Bold face values denote significance 𝑃<0.05. 𝑃= between 3 races.
^*P ^{a, b, c, d, e, f} = super scripts are significant 𝑃 values showing differences between AA and EA for post hoc analysis.
Continuous variables are expressed as mean ± SD, categorical variables are expressed as percentage.
Abbreviations: MAP: mean arterial pressure; Aortic PP: aortic pulse pressure; AIx75: augmentation index standardized to a heart rate of 75 beats/min; PWV: pulse wave velocity; FMD: flow-mediated dilation; SBP: systolic blood pressure; DBP: diastolic blood pressure.