Maternal Hyperglycemia Disrupts Histone 3 Lysine 36 Trimethylation of the IGF-1 Gene

Figure 5

Maternal hyperglycemia increased rat promoter 1 CpG methylation in females. (a) Rat promoter 1 CpG methylation in females. (b) Rat promoter 2 CpG methylation in females. (c) Rat promoter 1 CpG methylation in males. (d) Rat promoter 2 CpG methylation in males. All data were expressed as mean percent of methylation ± standard error of the mean, 𝑛=4 CON female, 𝑛=3 OHM female, 𝑛=5 CON male, and 𝑛=3 OHM male. *𝑃<0.05.

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