Timing of Maternal Exposure to a High Fat Diet and Development of Obesity and Hyperinsulinemia in Male Rat Offspring: Same Metabolic Phenotype, Different Developmental Pathways?

Figure 3

Pancreatic mRNA expression in adult CONT, MHF, and PLHF offspring. SOCS3: suppressor of cytokine signaling 3; IRS: insulin receptor substrate; PDX1: pancreatic and duodenal homeobox 1; ObRb: full length leptin receptor; Ins: insulin; Kir6.2: potassium channel subunit. Data are means ± SEM, 𝑛 = 10–18 per group. *𝑃<0.05.

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