Pomegranate Polyphenols Lower Lipid Peroxidation in Adults with Type 2 Diabetes but Have No Effects in Healthy Volunteers: A Pilot Study

Table 3

Effects of POMx on blood glucose, blood pressure, and lipids¹.

Variables	Healthy controls (𝑛=9)		T2DM subjects (𝑛=8)
	Screen	Week 4	Screen	Week 4
Fasting glucose (mg/dL)	85.11±4.48	85.67±8.03	105.88±29.57	114.25±33.36
Mean blood glucose (mg/dL)	97.33±16.93	97.33±19.01	121.25±16.73	116.38±11.56
Hemoglobin A1C (%)	5.51±0.51	5.51±0.57	6.22±0.50	6.08±0.35
Glycosylated hemoglobin (%)	6.45±0.76	6.45±0.85	7.51±0.75	7.31±0.53
Insulin (U/L)	7.77±2.44	10.52±12.06	18.61±7.30	19.06±6.03
Systolic blood pressure (mmHg)	114.67±6.18	115.33±5.81	129.00±18.19	134.25±23.81
Diastolic blood pressure (mmHg)	71.33±7.37	72.67±9.25	81.63±8.25	79.88±5.17
Total cholesterol (mg/dL)	187.89±30.16	195.56±30.53	182.13±40.47	181.50±36.73
Triglycerides (mg/dL)	77.11±18.43	77.56±26.88	149.75±94.73	135.63±66.06
LDL-cholesterol (mg/dL)	109.22±27.87	117.22±30.05	87.50±43.09	103.75±27.42
HDL-cholesterol (mg/dL)	63.11±7.56	62.89±9.35	51.75±11.45	50.38±11.03
VLDL-cholesterol (mg/dL)	15.33±3.67	15.44±5.29	30.00±19.04	27.25±13.32
LDL/HDL ratio	1.76±0.52	1.93±0.66	1.98±0.68	2.15±0.75
Total cholesterol/HDL ratio	2.89±0.78	3.05±0.88	3.63±0.92	3.58±0.96

1Data are mean ± SD; T2DM: type 2 diabetes mellitus.