Review Article
Immobilization Technologies in Probiotic Food Production
Table 3
Criteria used to define a probiotic microorganism.
| Safety criteria | Be of human origin | Nonpathogenic in nature | Generally recognized as safe (GRAS) |
| Functional criteria | Be resistant to destruction by gastric acid and bile salts | Adhere to intestinal epithelial tissue | Be able to colonize the gastrointestinal tract, even in the short term | Modulate immune responses | Produce antimicrobial substances | Influence human metabolic activities (i.e., cholesterol assimilation, lactase activity, vitamin production, etc.) |
| Technological criteria | Be resistant to destruction by technical processing | Be subjected to scale-up processes |
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