Maternal Fructose Intake Induces Insulin Resistance and Oxidative Stress in Male, but Not Female, Offspring

Figure 1

Fructose in pregnancy produces insulin resistance and hyperleptinemia in progeny. Male and female (a) HOMA-IR and (b) ISI ratios and (c) leptinemia of 24-hour fasted 90-day-old progeny from control, fructose-fed, and glucose-fed pregnant rats. Data are means ± SE; –12 animals from four litters. Different letters indicate significant differences between the groups ().

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(b)

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