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Journal of Nutrition and Metabolism
Volume 2016, Article ID 1373060, 13 pages
http://dx.doi.org/10.1155/2016/1373060
Clinical Study

Enteral Glutamine Administration in Critically Ill Nonseptic Patients Does Not Trigger Arginine Synthesis

1Department of Internal Medicine, VU University Medical Center, 1081 HV Amsterdam, Netherlands
2Department of Surgery, VU University Medical Center, 1081 HV Amsterdam, Netherlands
3Department of Intensive Care Unit, VU University Medical Center, 1081 HV Amsterdam, Netherlands
4Intensive Care Unit, Medisch Spectrum Twente, 7511 JX Enschede, Netherlands
5Department of Clinical Pharmacology and Pharmacy, VU University Medical Center, 1081 HV Amsterdam, Netherlands
6Department of Surgery, Medical Center Alkmaar and Trial Center Holland Health, Alkmaar, Netherlands
7Department of Pediatrics, VU University Medical Center, 1081 HV Amsterdam, Netherlands
8Department of Pediatrics, Emma Children’s Hospital, AMC, 1105 AZ Amsterdam, Netherlands

Received 24 October 2015; Revised 10 February 2016; Accepted 21 February 2016

Academic Editor: Najat Mokhtar

Copyright © 2016 Mechteld A. R. Vermeulen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Table S1 displays complete amino acid content and composition of the different enteral formulas used, expressed in g/L.

Figures S1A, S1B, and S1C show steady states achieved for GLN M+1, CIT M+5 and ARG M+2. Figures show TTR% in CON and ALA-GLN (DIPEP); when enterally and intravenously administered.

  1. Supplementary Material