Table of Contents Author Guidelines Submit a Manuscript
Journal of Nutrition and Metabolism
Volume 2016, Article ID 2867470, 13 pages
http://dx.doi.org/10.1155/2016/2867470
Review Article

Potential Benefits of Jujube (Zizyphus Lotus L.) Bioactive Compounds for Nutrition and Health

Department of Pharmacy, Research Group “Integrated Cellular Renewal and Microenvironment”, MERCI UPRES EA 3829, University of Rouen, 76183 Rouen Cedex, France

Received 13 July 2016; Accepted 23 October 2016

Academic Editor: C. S. Johnston

Copyright © 2016 Souleymane Abdoul-Azize. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. Maraghni, M. Gorai, and M. Neffati, “Seed germination at different temperatures and water stress levels, and seedling emergence from different depths of Ziziphus lotus,” South African Journal of Botany, vol. 76, no. 3, pp. 453–459, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. J. E. Richardson, L. W. Chatrou, J. B. Mols, R. H. J. Erkens, and M. D. Pirie, “Historical biogeography of two cosmopolitan families of flowering plants: annonaceae and rhamnaceae,” Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 359, no. 1450, pp. 1495–1508, 2004. View at Publisher · View at Google Scholar
  3. M. Gorai, M. Maraghni, and M. Neffati, “TPED Relationship between phenological traits and water potential patterns of the wild jujube Ziziphus lotus (L.) Lam. in southern Tunisia,” Plant Ecology and Diversity, vol. 3, no. 3, pp. 273–280, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Adeli and V. Samavati, “Studies on the steady shear flow behavior and chemical properties of water-soluble polysaccharide from Ziziphus lotus fruit,” International Journal of Biological Macromolecules, vol. 72, pp. 580–587, 2015. View at Publisher · View at Google Scholar · View at Scopus
  5. A. G. Pottier, Flora of Tunisia Angiospermes-Dicotyledones, Apetales-Dialypetales. Programme Flore et Végétation Tunisiennes, Ministère de l’Enseignement Supérieur et de la Recherche Scientifique et le Ministère de l’Agriculture, Tunis, Tunisia, 1981.
  6. B. Adzu, S. Amos, M. B. Amizan, and K. Gamaniel, “Evaluation of the antidiarrhoeal effects of Zizyphus spina-christi stem bark in rats,” Acta Tropica, vol. 87, no. 2, pp. 245–250, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Lahlou, M. El Mahi, and J. Hamamouchi, “Evaluation of antifungal and molluscicidal activities of Moroccan Zizyphus lotus (L.) Desf,” Annales Pharmaceutiques Francaises, vol. 60, no. 6, pp. 410–414, 2002. View at Google Scholar · View at Scopus
  8. E. Le-Floc'h, Contribution à une Étude Ethnobotanique de la Flore de la Tunisie: Programme Flore et Végétation Tunisienne, Publications Scientifiques Tunisiennes, 1983.
  9. K. K. Anand, B. Singh, D. Grand, B. K. Chandan, and V. N. Gupta, “Effect of Zizyphus sativa leaves on blood glucose levels in normal and alloxan-diabetic rats,” Journal of Ethnopharmacology, vol. 27, no. 1-2, pp. 121–127, 1989. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Elaloui, A. Laamouri, A. Albouchi et al., “Chemical compositions of the tunisian Ziziphus jujuba oil,” Emirates Journal of Food and Agriculture, vol. 26, no. 7, pp. 602–608, 2014. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Chouaibi, N. Mahfoudhi, L. Rezig, F. Donsì, G. Ferrari, and S. Hamdi, “Nutritional composition of Zizyphus lotus L. seeds,” Journal of the Science of Food and Agriculture, vol. 92, no. 6, pp. 1171–1177, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. J.-H. Renault, K. Ghedira, P. Thepenier, C. Lavaud, M. Zeches-Hanrot, and L. Le Men-Olivier, “Dammarane saponins from Zizyphus lotus,” Phytochemistry, vol. 44, no. 7, pp. 1321–1327, 1997. View at Publisher · View at Google Scholar · View at Scopus
  13. H. Ghazghazi, C. Aouadhi, L. Riahi, A. Maaroufi, and B. Hasnaoui, “Fatty acids composition of Tunisian Ziziphus lotus L. (Desf.) fruits and variation in biological activities between leaf and fruit extracts,” Natural Product Research, vol. 28, no. 14, pp. 1106–1110, 2014. View at Publisher · View at Google Scholar · View at Scopus
  14. S. Abdoul-Azize, M. Bendahmane, A. Hichami et al., “Effects of Zizyphus lotus L. (Desf.) polyphenols on Jurkat cell signaling and proliferation,” International Immunopharmacology, vol. 15, no. 2, pp. 364–371, 2013. View at Publisher · View at Google Scholar · View at Scopus
  15. K. Ghedira, R. Chemli, B. Richard, J.-M. Nuzillard, M. Zeches, and L. Le Men-Olivier, “Two cyclopeptide alkaloids from Zizyphus lotus,” Phytochemistry, vol. 32, no. 6, pp. 1591–1594, 1993. View at Publisher · View at Google Scholar · View at Scopus
  16. K. Ghedira, R. Chemli, C. Caron, J.-M. Nuzilard, M. Zeches, and L. Le Men-Olivier, “Four cyclopeptide alkaloids from Zizyphus lotus,” Phytochemistry, vol. 38, no. 3, pp. 767–772, 1995. View at Publisher · View at Google Scholar · View at Scopus
  17. G. Le Crouéour, P. Thépenier, B. Richard, C. Petermann, K. Ghédira, and M. Zèches-Hanrot, “Lotusine G: a new cyclopeptide alkaloid from Zizyphus lotus,” Fitoterapia, vol. 73, no. 1, pp. 63–68, 2002. View at Publisher · View at Google Scholar · View at Scopus
  18. W. Borgi, M.-C. Recio, J. L. Ríos, and N. Chouchane, “Anti-inflammatory and analgesic activities of flavonoid and saponin fractions from Zizyphus lotus (L.) Lam.,” South African Journal of Botany, vol. 74, no. 2, pp. 320–324, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Abdeddaim, O. Lombarkia, A. Bacha et al., “Biochemical characterization and nutritional properties of Zizyphus lotus l. fruits in aures region, northeastern of Algeria,” Food Science and Technology, vol. 15, pp. 75–81, 2014. View at Google Scholar
  20. A. Maciuk, C. Lavaud, P. Thépenier, M.-J. Jacquier, K. Ghédira, and M. Zèches-Hanrot, “Four new dammarane saponins from Zizyphus lotus,” Journal of Natural Products, vol. 67, no. 10, pp. 1639–1643, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. F.-Z. Bakhtaoui, H. Lakmichi, F. Megraud, A. Chait, and C.-E. A. Gadhi, “Gastro-protective, anti-Helicobacter pylori and, antioxidant properties of Moroccan Zizyphus lotus L,” Journal of Applied Pharmaceutical Science, vol. 4, no. 10, pp. 81–87, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. C. Benammar, C. Baghdad, M. Belarbi, S. Subramaniam, A. Hichami, and N. A. Khan, “Antidiabetic and antioxidant activities of Zizyphus lotus L aqueous extracts in Wistar rats,” Journal of Nutrition & Food Sciences, 2014. View at Publisher · View at Google Scholar
  23. K. M. Hammi, A. Jdey, C. Abdelly, H. Majdoub, and R. Ksouri, “Optimization of ultrasound-assisted extraction of antioxidant compounds from Tunisian Zizyphus lotus fruits using response surface methodology,” Food Chemistry, vol. 184, pp. 80–89, 2015. View at Publisher · View at Google Scholar
  24. M. Ghalem, S. Merghache, and M. Belarbi, “Study on the antioxidant activities of root extracts of Zizyphus lotus from the western region of Algeria,” Pharmacognosy Journal, vol. 6, no. 4, pp. 32–42, 2014. View at Publisher · View at Google Scholar · View at Scopus
  25. N. Rsaissi, EL Kamili, B. Bencharki, L. Hillali, and M. Bouhache, “Antimicrobial activity of fruits extracts of the wild jujube ‘Ziziphus Lotus (L.) Desf.,” International Journal of Scientific & Engineering Research, vol. 4, pp. 1521–1528, 2013. View at Google Scholar
  26. B. Boulanouar, G. Abdelaziz, S. Aazza, C. Gago, and M. G. Miguel, “Antioxidant activities of eight Algerian plant extracts and two essential oils,” Industrial Crops and Products, vol. 46, pp. 85–96, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. B. Wahida, B. Abderrahman, and C. Nabil, “Antiulcerogenic activity of Zizyphus lotus (L.) extracts,” Journal of Ethnopharmacology, vol. 112, no. 2, pp. 228–231, 2007. View at Publisher · View at Google Scholar · View at Scopus
  28. C. Benammar, A. Hichami, A. Yessoufou et al., “Zizyphus lotus L. (Desf.) modulates antioxidant activity and human T-cell proliferation,” BMC Complementary and Alternative Medicine, vol. 10, article 54, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. A. Maciuk, K. Ghedira, P. Thepenier, C. Lavaud, and M. Zeches-Hanrot, “A new flavonol glycoside from leaves of Zizyphus lotus,” Pharmazie, vol. 58, no. 2, pp. 158–159, 2003. View at Google Scholar · View at Scopus
  30. F. Benkhalti, J. Prost, E. Paz, F. Perez-Jimenez, C. El Modafar, and E. El Boustani, “Effects of feeding virgin olive oil or their polyphenols on lipid of rat liver,” Nutrition Research, vol. 22, no. 9, pp. 1067–1075, 2002. View at Publisher · View at Google Scholar · View at Scopus
  31. H. Tapiero, K. D. Tew, G. Nguyen Ba, and G. Mathé, “Polyphenols: do they play a role in the prevention of human pathologies?” Biomedicine and Pharmacotherapy, vol. 56, no. 4, pp. 200–207, 2002. View at Publisher · View at Google Scholar · View at Scopus
  32. W. Borgi and N. Chouchane, “Anti-spasmodic effects of Zizyphus lotus (L.) Desf. extracts on isolated rat duodenum,” Journal of Ethnopharmacology, vol. 126, no. 3, pp. 571–573, 2009. View at Publisher · View at Google Scholar · View at Scopus
  33. B. A. Sutherland, R. M. A. Rahman, and I. Appleton, “Mechanisms of action of green tea catechins, with a focus on ischemia-induced neurodegeneration,” Journal of Nutritional Biochemistry, vol. 17, no. 5, pp. 291–306, 2006. View at Publisher · View at Google Scholar · View at Scopus
  34. R. Leenen, A. J. C. Roodenburg, L. B. M. Tijburg, and S. A. Wiseman, “A single dose of tea with or without milk increases plasma antioxidant activity in humans,” European Journal of Clinical Nutrition, vol. 54, no. 1, pp. 87–92, 2000. View at Publisher · View at Google Scholar · View at Scopus
  35. J. Martinez and J. J. Moreno, “Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production,” Biochemical Pharmacology, vol. 59, no. 7, pp. 865–870, 2000. View at Publisher · View at Google Scholar · View at Scopus
  36. J. Bajerska, M. Wozniewicz, J. Jeszka, S. Drzymala-Czyz, and J. Walkowiak, “Green tea aqueous extract reduces visceral fat and decreases protein availability in rats fed with a high-fat diet,” Nutrition Research, vol. 31, no. 2, pp. 157–164, 2011. View at Publisher · View at Google Scholar · View at Scopus
  37. N. Ahmad, P. Cheng, and H. Mukhtar, “Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate,” Biochemical and Biophysical Research Communications, vol. 275, no. 2, pp. 328–334, 2000. View at Publisher · View at Google Scholar · View at Scopus
  38. F. Ren, S. Zhang, S. H. Mitchell, R. Butler, and C. Y. F. Young, “Tea polyphenols down-regulate the expression of the androgen receptor in LNCaP prostate cancer cells,” Oncogene, vol. 19, no. 15, pp. 1924–1932, 2000. View at Publisher · View at Google Scholar · View at Scopus
  39. Y.-C. Liang, S.-Y. Lin-Shiau, C.-F. Chen, and J.-K. Lin, “Suppression of extracellular signals and cell proliferation through EGF receptor binding by (−)-epigallocatechin gallate in human A431 epidermoid carcinoma cells,” Journal of Cellular Biochemistry, vol. 67, no. 1, pp. 55–65, 1997. View at Publisher · View at Google Scholar · View at Scopus
  40. D. O. Kennedy, S. Nishimura, T. Hasuma, Y. Yano, S. Otani, and I. Matsui-Yuasa, “Involvement of protein tyrosine phosphorylation in the effect of green tea polyphenols on Ehrlich ascites tumor cells in vitro,” Chemico-Biological Interactions, vol. 110, no. 3, pp. 159–172, 1998. View at Publisher · View at Google Scholar · View at Scopus
  41. D. Ollivier, J. Artaud, C. Pinatel, J. P. Durbec, and M. Guérère, “Triacylglycerol and fatty acid compositions of French virgin olive oils. Characterization by chemometrics,” Journal of Agricultural and Food Chemistry, vol. 51, no. 19, pp. 5723–5731, 2003. View at Publisher · View at Google Scholar · View at Scopus
  42. R. Marfil, C. Cabrera-Vique, R. Giménez, P. R. Bouzas, O. Martínez, and J. A. Sánchez, “Metal content and physicochemical parameters used as quality criteria in virgin argan oil: influence of the extraction method,” Journal of Agricultural and Food Chemistry, vol. 56, no. 16, pp. 7279–7284, 2008. View at Publisher · View at Google Scholar · View at Scopus
  43. F. O. Ayorinde, K. Garvin, and K. Saeed, “Determination of the fatty acid composition of saponified vegetable oils using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry,” Rapid Communications in Mass Spectrometry, vol. 14, no. 7, pp. 608–615, 2000. View at Publisher · View at Google Scholar · View at Scopus
  44. I. J. Karoui, W. A. Wannes, and B. Marzouk, “Refined corn oil aromatization by Citrus aurantium peel essential oil,” Industrial Crops and Products, vol. 32, no. 3, pp. 202–207, 2010. View at Publisher · View at Google Scholar · View at Scopus
  45. J. J. Ochoa, J. L. Quiles, M. C. Ramírez-Tortosa, J. Mataix, and J. R. Huertas, “Dietary oils high in oleic acid but with different unsaponifiable fraction contents have different effects in fatty acid composition and peroxidation in rabbit LDL,” Nutrition, vol. 18, no. 1, pp. 60–65, 2002. View at Publisher · View at Google Scholar · View at Scopus
  46. B. Aspenström-Fagerlund, J. Tallkvist, N.-G. Ilbäck, and A. W. Glynn, “Oleic acid increases intestinal absorption of the BCRP/ABCG2 substrate, mitoxantrone, in mice,” Toxicology Letters, vol. 237, no. 2, pp. 133–139, 2015. View at Publisher · View at Google Scholar · View at Scopus
  47. S. M. Soel, O. S. Choi, M. H. Bang, J. H. Yoon Park, and W. K. Kim, “Influence of conjugated linoleic acid isomers on the metastasis of colon cancer cells in vitro and in vivo,” Journal of Nutritional Biochemistry, vol. 18, no. 10, pp. 650–657, 2007. View at Publisher · View at Google Scholar · View at Scopus
  48. M. F. Ramadan and J.-T. Moersel, “Lipid profile of prickly pear pulp fractions,” Journal of Food, Agriculture and Environment, vol. 1, pp. 66–70, 2003. View at Google Scholar
  49. M. F. Ramadan and J.-T. Mörsel, “Oil cactus pear (Opuntia ficus-indica L.),” Food Chemistry, vol. 82, no. 3, pp. 339–345, 2003. View at Publisher · View at Google Scholar · View at Scopus
  50. S. Abidi, H. Ben Salem, V. Vasta, and A. Priolo, “Supplementation with barley or spineless cactus (Opuntia ficus indica f. inermis) cladodes on digestion, growth and intramuscular fatty acid composition in sheep and goats receiving oaten hay,” Small Ruminant Research, vol. 87, no. 1–3, pp. 9–16, 2009. View at Publisher · View at Google Scholar · View at Scopus
  51. M. Rubio, M. Alvarez-Ortí, A. S. Alvarruiz, E. Fernández, and J. E. Pardo, “Characterization of oil obtained from grape seeds collected during berry development,” Journal of Agricultural and Food Chemistry, vol. 57, no. 7, pp. 2812–2815, 2009. View at Publisher · View at Google Scholar · View at Scopus
  52. S. Filip, J. Hribar, and R. Vidrih, “Influence of natural antioxidants on the formation of trans-fatty-acid isomers during heat treatment of sunflower oil,” European Journal of Lipid Science and Technology, vol. 113, no. 2, pp. 224–230, 2011. View at Publisher · View at Google Scholar · View at Scopus
  53. I. A. Nehdi, H. M. Sbihi, C. P. Tan, and S. I. Al-Resayes, “Seed oil from Harmal (Rhazya stricta Decne) grown in Riyadh (Saudi Arabia): a potential source of δ-tocopherol,” Journal of Saudi Chemical Society, vol. 20, no. 1, pp. 107–113, 2016. View at Publisher · View at Google Scholar · View at Scopus
  54. M. El Aloui, K. Mguis, A. Laamouri et al., “Fatty acid and sterol oil composition of four Tunisian ecotypes of Ziziphus zizyphus (L.) H.Karst,” Acta Botanica Gallica, vol. 159, no. 1, pp. 25–31, 2012. View at Publisher · View at Google Scholar · View at Scopus
  55. S. Boudraa, L. Hambaba, S. Zidani, and H. Boudraa, “Mineral and vitamin composition of fruits of five underexploited species in Algeria: Celtis australis L., Crataegus azarolus L., Crataegus monogyna Jacq., Elaeagnus angustifolia L. and Zizyphus lotus L,” Fruits, vol. 65, no. 2, pp. 75–84, 2010. View at Publisher · View at Google Scholar · View at Scopus
  56. W. E. Neff, T. L. Mounts, W. M. Rinsch, and H. Konishi, “Photooxidation of soybean oils as affected by triacylglycerol composition and structure,” Journal of the American Oil Chemists' Society, vol. 70, no. 2, pp. 163–168, 1993. View at Publisher · View at Google Scholar · View at Scopus
  57. W. E. Neff, T. L. Mounts, W. M. Rinsch, H. Konishi, and M. A. El-Agaimy, “Oxidative stability of purified canola oil triacylglycerols with altered fatty acid compositions as affected by triacylglycerol composition and structure,” Journal of the American Oil Chemists' Society, vol. 71, no. 10, pp. 1101–1109, 1994. View at Publisher · View at Google Scholar
  58. F. Ntanios, “Plant sterol-ester-enriched spreads as an example of a new functional food,” European Journal of Lipid Science and Technology, vol. 103, no. 2, pp. 102–106, 2001. View at Publisher · View at Google Scholar · View at Scopus
  59. M. D. Salvador, F. Aranda, S. Gómez-Alonso, and G. Fregapane, “Cornicabra virgin olive oil: a study of five crop seasons. Composition, quality and oxidative stability,” Food Chemistry, vol. 74, no. 3, pp. 267–274, 2001. View at Publisher · View at Google Scholar · View at Scopus
  60. M. Guderjan, S. Tôpfl, A. Angersbach, and D. Knorr, “Impact of pulsed electric field treatment on the recovery and quality of plant oils,” Journal of Food Engineering, vol. 67, no. 3, pp. 281–287, 2005. View at Publisher · View at Google Scholar · View at Scopus
  61. J. Bellakhdar, La Pharmacopée Marocaine Traditionnelle, Ibis Press, Paris, France, 1997.
  62. W. Borgi, K. Ghedira, and N. Chouchane, “Antiinflammatory and analgesic activities of Zizyphus lotus root barks,” Fitoterapia, vol. 78, no. 1, pp. 16–19, 2007. View at Publisher · View at Google Scholar · View at Scopus
  63. K. Boukef, Les Plantes Dans la Médicine Traditionnelle Tunisienne: Medicine Traditionnelle et Pharmacopée, Agence de Coopération Culturelle et Technique, Paris, France, 1986.
  64. K. Ghedira, “Zizyphus lotus (L.) Desf. (Rhamnaceae): jujubier sauvage,” Phytothérapie, vol. 11, no. 3, pp. 149–153, 2013. View at Publisher · View at Google Scholar · View at Scopus
  65. T. A. Van Beek, A. M. Deelder, R. Verpoorte, and A. Baerheim Svendsen, “Antimicrobial, antiamoebic and antiviral screening of some Tabernaemontana species,” Planta Medica, vol. 50, no. 2, pp. 180–185, 1984. View at Publisher · View at Google Scholar · View at Scopus
  66. V. B. Pandey and S. Devi, “Biologically active cyclopeptide alkaloids from Rhamnaceae plants,” Planta Medica, vol. 56, no. 6, pp. 649–650, 1990. View at Google Scholar · View at Scopus
  67. J.-W. Li, L.-P. Fan, S.-D. Ding, and X.-L. Ding, “Nutritional composition of five cultivars of Chinese jujube,” Food Chemistry, vol. 103, no. 2, pp. 454–460, 2007. View at Publisher · View at Google Scholar · View at Scopus
  68. W. N. Sawaya, J. K. Khalil, and M. M. Al-Mohammad, “Nutritive value of prickly pear seeds, Opuntia ficus-indica,” Plant Foods for Human Nutrition, vol. 33, no. 1, pp. 91–97, 1983. View at Publisher · View at Google Scholar · View at Scopus
  69. R. A. A. Mothana, “Anti-inflammatory, antinociceptive and antioxidant activities of the endemic Soqotraen Boswellia elongata Balf. f. and Jatropha unicostata Balf. f. in different experimental models,” Food and Chemical Toxicology, vol. 49, no. 10, pp. 2594–2599, 2011. View at Publisher · View at Google Scholar · View at Scopus
  70. L. A. S. Brown, F. L. Harris, X.-D. Ping, and T. W. Gauthier, “Chronic ethanol ingestion and the risk of acute lung injury: a role for glutathione availability?” Alcohol, vol. 33, no. 3, pp. 191–197, 2004. View at Publisher · View at Google Scholar · View at Scopus
  71. N. H. Aziz, S. E. Farag, L. A. A. Mousa, and M. A. Abo-Zaid, “Comparative antibacterial and antifungal effects of some phenolic compounds,” Microbios, vol. 93, no. 374, pp. 43–54, 1998. View at Google Scholar · View at Scopus
  72. A. O. Abdel-Zaher, S. Y. Salim, M. H. Assaf, and R. H. Abdel-Hady, “Antidiabetic activity and toxicity of Zizyphus spina-christi leaves,” Journal of Ethnopharmacology, vol. 101, no. 1–3, pp. 129–138, 2005. View at Publisher · View at Google Scholar · View at Scopus
  73. S. M. Jeyakumar, P. Vijaya Kumar, N. V. Giridharan, and A. Vajreswari, “Vitamin A improves insulin sensitivity by increasing insulin receptor phosphorylation through protein tyrosine phosphatase 1B regulation at early age in obese rats of WNIN/Ob strain,” Diabetes, Obesity and Metabolism, vol. 13, no. 10, pp. 955–958, 2011. View at Publisher · View at Google Scholar · View at Scopus
  74. R. K. Sundaram, A. Bhaskar, S. Vijayalingam, M. Viswanathan, R. Mohan, and K. R. Shanmugasundaram, “Antioxidant status and lipid peroxidation in type II diabetes mellitus with and without complications,” Clinical Science, vol. 90, no. 4, pp. 255–260, 1996. View at Publisher · View at Google Scholar · View at Scopus
  75. M. Shadman, Z. Rajabian, A. Ajami et al., “Frequency of γδ T cells and invariant natural killer T cells in Helicobacter pylori-infected patients with peptic ulcer and gastric cancer,” Iranian Journal of Allergy, Asthma and Immunology, vol. 14, no. 5, pp. 493–501, 2015. View at Google Scholar · View at Scopus
  76. A. M. Costa, R. M. Ferreira, I. Pinto-Ribeiro et al., “Helicobacter pylori activates matrix metalloproteinase-10 in gastric epithelial cells via EGFR and ERK-mediated pathways,” Journal of Infectious Diseases, vol. 213, no. 11, pp. 1767–1776, 2016. View at Publisher · View at Google Scholar
  77. C. Zhang, H. Yu, H. Xu, and L. Yang, “Expression of secreted phospholipase A2-Group IIA correlates with prognosis of gastric adenocarcinoma,” Oncology Letters, vol. 10, no. 5, pp. 3050–3058, 2015. View at Publisher · View at Google Scholar · View at Scopus
  78. M. Fassan, D. Saraggi, L. Balsamo et al., “Let-7c down-regulation in Helicobacter pylori-related gastric carcinogenesis,” Oncotarget, vol. 7, no. 4, pp. 4915–4924, 2016. View at Publisher · View at Google Scholar · View at Scopus
  79. R. Yuge, Y. Kitadai, S. Tanaka et al., “Regression of cecal MALT lymphoma after antibiotic treatment in a patient with Helicobacter pylori infection,” Internal Medicine, vol. 55, no. 2, pp. 135–139, 2016. View at Publisher · View at Google Scholar · View at Scopus