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Journal of Nutrition and Metabolism
Volume 2016, Article ID 3910630, 9 pages
Clinical Study

Effects of Dietary Strawberry Supplementation on Antioxidant Biomarkers in Obese Adults with Above Optimal Serum Lipids

1Department of Nutritional Sciences, College of Human Sciences, Oklahoma State University, Stillwater, OK 74078, USA
2Centre for Experimental Medicine, Queen’s University of Belfast, Belfast BT7 1NN, UK
3Section of Diabetes & Endocrinology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA

Received 2 March 2016; Accepted 19 May 2016

Academic Editor: Stan Kubow

Copyright © 2016 Arpita Basu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Berries have shown several cardiovascular health benefits and have been associated with antioxidant functions in experimental models. Clinical studies are limited. We examined the antioxidant effects of freeze-dried strawberries (FDS) in adults [; age: years; BMI:  kg/m2 (mean ± SD)] with abdominal adiposity and elevated serum lipids. Participants were randomized to one of the following arms: low dose strawberry (25 g/day FDS), low dose control beverage (LD-C), high dose strawberry (50 g/d FDS), and high dose control beverage (HD-C) for 12 weeks. Control beverages were matched for calories and total fiber. Plasma antioxidant capacity, trace elements (copper, iron, selenium, and zinc), whole blood glutathione (GSH), and enzyme activity (catalase, glutathione peroxidase, and glutathione reductase) were examined at screening (0 week) and after 12 weeks’ intervention. At 12 weeks, plasma antioxidant capacity and glutathione levels were higher in the strawberry versus control groups (low and high dose FDS: 45% and 42% for plasma antioxidant capacity and 28% and 36% for glutathione, resp.); glutathione was higher in the high versus low dose strawberry group (all ). Serum catalase activity was higher in the low dose strawberry (43%) versus control group (). No differences were noted in plasma trace elements and glutathione enzyme activity. Dietary strawberries may selectively increase plasma antioxidant biomarkers in obese adults with elevated lipids.