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Journal of Nutrition and Metabolism
Volume 2017, Article ID 4798963, 10 pages
https://doi.org/10.1155/2017/4798963
Research Article

A Moderate Zinc Deficiency Does Not Alter Lipid and Fatty Acid Composition in the Liver of Weanling Rats Fed Diets Rich in Cocoa Butter or Safflower Oil

Institute of Nutritional Physiology and Animal Nutrition, Justus Liebig University, Heinrich-Buff-Ring 29-32, 35392 Giessen, Germany

Correspondence should be addressed to Edgar Weigand; ed.nesseig-inu.gnurheanre@dnagiew.ragde

Received 17 October 2016; Revised 8 March 2017; Accepted 19 March 2017; Published 29 March 2017

Academic Editor: H. K. Biesalski

Copyright © 2017 Edgar Weigand and Jennifer Egenolf. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aim of the study was to examine whether a moderate zinc deficiency alters hepatic lipid composition. Male weanling rats, assigned to five groups (8 animals each), were fed low-carbohydrate high-fat diets supplemented with 7 or 50 mg Zn/kg (LZ or HZ) and 22% cocoa butter (CB) or 22% safflower oil (SF) for four weeks. One group each had free access to the LZ-CB and LZ-SF diets, one group each was restrictedly fed the HZ-CB and HZ-SF diets in matching amounts, and one group had free access to the HZ-SF diet (ad libitum control). The rats fed the LZ diets had significantly lower energy intakes and final body weights than the ad libitum control group, and lower plasma and femur Zn concentrations than the animals consuming the HZ diets. Hepatic cholesterol, triacylglycerol and phospholipid concentrations, and fatty acid composition of hepatic triacylglycerols and phospholipids did not significantly differ between the LZ and their respective HZ groups, but were greatly affected by dietary fat source. In conclusion, the moderate Zn deficiency did not significantly alter liver lipid concentrations and fatty acid composition.