| (1) | Similar total dietary intakes of most micronutrients when participants consumed AA-MF or Glytactin GMP-MF and no differences in intakes of micronutrients from natural foods were observed. Thus, differences in micronutrient intakes were driven by the diverse micronutrient supplementation profiles of the medical foods. |
| (2) | Participants obtained adequate intakes (≥EAR) of most micronutrients. However, inadequate intakes (i.e., <EAR) of potassium for 93% of participants and choline for >40% of participants were observed. |
| (3) | Participants had excessive intakes (>UL) of chemically derived folic acid and magnesium from medical foods, and >63% of participants had excessive intakes of sodium driven by natural (likely processed) food intake. Average sugar intake as a percentage of energy was 27% and was excessive (>DGA) for 97% of participants. |
| (4) | Without micronutrient supplementation of medical foods, >70% of participants would have inadequate intakes (≤EAR) for 11 micronutrients (biotin, choline, pantothenate, vitamins D and E, potassium, calcium, iodine, magnesium, selenium, and zinc). Greater than 90% of participants would obtain adequate intake (≥EAR) of vitamin A from natural foods alone due to high intakes of provitamin A carotenoids from green leafy vegetables, squashes, carrots, and tomatoes. |
| (5) | Of 30 participants, only 13 consumed MLPF with both AA-MF and GMP-MF treatments. MPLF comprised approximately 10% of median calories. |
| (6) | Increased urinary excretion of sulfate, taurine, and taurine-related metabolites with AA-MF may be related to increased need to excrete sulfur with higher dietary intake of sulfur-containing amino acids, Met and Cys, from AA-MF compared with Glytactin GMP-MF. |
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