Growth Patterns in the Irish Pyridoxine Nonresponsive Homocystinuria Population and the Influence of Metabolic Control and Protein Intake

Table 1

Metabolic control given as homocyst(e)ine, methionine, and cystine concentrations under treatment (µmol/L).

	Free Homocystine		Total homocysteine		Methionine		Cystine
	NBS	LD	NBS	LD	NBS	LD	NBS	LD
Number of samples	234	25	104	8	237	25	223	24
Mean	15.1	15.7	91.1	88.5	72.6	119.6	39	43
Median	9.5	5	79	71.5	62.5	99.2	31.5	35.3
Range	0–90	0–100	5–269	9–202	3–600	10–324	4–180	3–57
P value	P = 0.917		P = 0.933		P = 0.165		P = 0.660