Research Article
The Association between Obesity-Risk Genes and Gestational Weight Gain Is Modified by Dietary Intake in African American Women
Table 3
The effect of gene-diet interactions on gestational weight gain.
| | | Gestational weight gaina | | β | 95% confidence interval | | Pinteraction |
| Percentage of energy intake from fat | | −0.34 | −1.38 | 0.69 | 0.51 | | KCTD15 (rs11084753) | AG | 3.44 | 0.30 | 6.57 | 0.03 | | AA | −0.02 | −4.56 | 4.51 | 0.99 | | GG | Reference | | | | | Percentage of energy intake from fat × KCTD15 | AG | 1.80 | 0.35 | 3.25 | 0.02 | 0.048 | AA | 0.96 | −0.73 | 2.65 | 0.26 | | GG | Reference | | | | | Percentage of energy intake from carbohydrate | | −0.01 | −0.57 | 0.54 | 0.96 | | KCTD15 (rs11084753) | AG | 3.56 | 0.40 | 6.71 | 0.03 | | AA | −0.59 | −5.70 | 4.52 | 0.82 | | GG | Reference | | | | | Percentage of energy intake from carbohydrate × KCTD15 | AG | −0.80 | −1.57 | −0.03 | 0.04 | 0.10 | AA | −0.03 | −2.11 | 2.06 | 0.98 | | GG | Reference | | | | |
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aProcess model 1 adjusted for maternal age, smoking, marital status, prepregnancy BMI, parity, and illicit drug use.
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