Efficacy of an Anthocyanin and Prebiotic Blend on Intestinal Environment in Obese Male and Female Subjects
Table 4
Bowel habits in participants supplemented with the anthocyanin-prebiotic blend at baseline (day 0) and end of the study (day 57) ().
Bristol Stool Scale ()
Number of bowel movements (/day)
Proportion of bowel movements that were straining to start (%)
Proportion of bowel movements that were straining to stop (%)
Proportion of bowel movements that were incomplete (%)
Mean ± SD ()
Mean ± SD ()
Mean ± SD ()
Mean ± SD ()
Mean ± SD ()
Median (interquartile range)
Median (interquartile range)
Median (interquartile range)
Median (interquartile range)
Median (interquartile range)
Within-group valuea
Within-group valuea
Within-group valuea
Within-group valuea
Within-group valuea
Baseline
3.88 ± 0.79 (46)
2.52 ± 1.09 (46)
17.7 ± 22.8 (46)
3.9 ± 10.3 (46)
22.9 ± 27.5 (46)
3.87 (0.94)
2 (1)
6.7 (25.0)
0 (2.9)
11.4 (34.6)
Change from baseline to week 1
−0.01 ± 0.59 (46)
−0.07 ± 0.88 (46)
1.5 ± 20.7 (46)
−1.1 ± 8.2 (46)
−3.8 ± 23.9 (46)
0.04 (0.71)
0 (2)
0 (20.4)
0 (0)
0 (19.6)
0.924
0.709b
0.420b
0.185b
0.191b
Change from baseline to week 2
−0.00 ± 0.65 (46)
−0.28 ± 0.89 (46)
−1.1 ± 17.3 (46)
0.9 ± 9.6 (46)
−8.7 ± 22.5 (46)
−0.03 (0.64)
0 (1)
0 (13.0)
0 (0)
−4 (14.9)
0.994
0.066b
0.083b
0.345b
<0.001b
Change from baseline to week 3
0.10 ± 0.55 (46)
−0.17 ± 0.93 (46)
−2.5 ± 18.0 (46)
3.5 ± 16.1 (46)
−8.7 ± 24.9 (46)
0.14 (0.63)
0 (1)
0 (16.5)
0 (0)
−3.3 (16.2)
0.225
0.349b
0.089b
0.506b
<0.001b
Change from baseline to week 4
0.11 ± 0.70 (46)
0.04 ± 1.03 (46)
−3.7 ± 19.1 (46)
−1.2 ± 6.3 (46)
−10.9 ± 21.9 (46)
0.16 (0.82)
0 (2)
−0.8 (10.6)
0 (0)
−2.6 (17.8)
0.309
0.962b
0.004b
0.025b
<0.001b
Change from baseline to week 5
0.11 ± 0.54 (46)
−0.26 ± 0.80 (46)
−5.6 ± 18.0 (46)
0.5 ± 7.5 (46)
−10.7 ± 27.2 (46)
0.17 (0.64)
0 (1)
−3.9 (13.0)
0 (0)
−4.2 (20.0)
0.193
0.056b
0.002b
0.124b
<0.001b
Change from baseline to week 6
0.17 ± 0.58 (46)
0.02 ± 0.86 (46)
−4.8 ± 14.1 (46)
−1.2 ± 5.8 (46)
−11.6 ± 20.6 (46)
0.24 (0.65)
0 (0)
−4 (12.8)
0 (0)
−4.5 (21.1)
0.051
0.891b
<0.001b
0.167b
<0.001b
Change from baseline to week 7
0.18 ± 0.53 (46)
−0.15 ± 0.73 (46)
−5.0 ± 16.9 (46)
−2.0 ± 7.4 (46)
−11.6 ± 24.2 (46)
0.22 (0.67)
0 (1)
0 (14.1)
0 (0)
−6.7 (21.1)
0.028
0.284b
0.002b
0.046b
<0.001b
Change from baseline to week 8
0.18 ± 0.64 (46)
−0.07 ± 0.95 (46)
−5.6 ± 19.1 (46)
−2.2 ± 8.3 (46)
−27 ± 108 (46)
0.28 (0.81)
0 (1.75)
−1.7 (14.0)
0 (2.9)
−6 (21.7)
0.063
0.432b
<0.001b
0.019b
<0.001b
n: number; SD: standard deviation. aWithin-group comparisons were made using the paired Student’s t-test. bLogarithmic transformation required to achieve normality. Probability values ≤0.05 are statistically significant.