Clinical Study

Efficacy of an Anthocyanin and Prebiotic Blend on Intestinal Environment in Obese Male and Female Subjects

Table 4

Bowel habits in participants supplemented with the anthocyanin-prebiotic blend at baseline (day 0) and end of the study (day 57) ().

Bristol Stool Scale ()Number of bowel movements (/day)Proportion of bowel movements that were straining to start (%)Proportion of bowel movements that were straining to stop (%)Proportion of bowel movements that were incomplete (%)
Mean ± SD ()Mean ± SD ()Mean ± SD ()Mean ± SD ()Mean ± SD ()
Median (interquartile range)Median (interquartile range)Median (interquartile range)Median (interquartile range)Median (interquartile range)
Within-group valueaWithin-group valueaWithin-group valueaWithin-group valueaWithin-group valuea

Baseline3.88 ± 0.79 (46)2.52 ± 1.09 (46)17.7 ± 22.8 (46)3.9 ± 10.3 (46)22.9 ± 27.5 (46)
3.87 (0.94)2 (1)6.7 (25.0)0 (2.9)11.4 (34.6)

Change from baseline to week 1−0.01 ± 0.59 (46)−0.07 ± 0.88 (46)1.5 ± 20.7 (46)−1.1 ± 8.2 (46)−3.8 ± 23.9 (46)
0.04 (0.71)0 (2)0 (20.4)0 (0)0 (19.6)
0.9240.709b0.420b0.185b0.191b

Change from baseline to week 2−0.00 ± 0.65 (46)−0.28 ± 0.89 (46)−1.1 ± 17.3 (46)0.9 ± 9.6 (46)−8.7 ± 22.5 (46)
−0.03 (0.64)0 (1)0 (13.0)0 (0)−4 (14.9)
0.9940.066b0.083b0.345b<0.001b

Change from baseline to week 30.10 ± 0.55 (46)−0.17 ± 0.93 (46)−2.5 ± 18.0 (46)3.5 ± 16.1 (46)−8.7 ± 24.9 (46)
0.14 (0.63)0 (1)0 (16.5)0 (0)−3.3 (16.2)
0.2250.349b0.089b0.506b<0.001b

Change from baseline to week 40.11 ± 0.70 (46)0.04 ± 1.03 (46)−3.7 ± 19.1 (46)−1.2 ± 6.3 (46)−10.9 ± 21.9 (46)
0.16 (0.82)0 (2)−0.8 (10.6)0 (0)−2.6 (17.8)
0.3090.962b0.004b0.025b<0.001b

Change from baseline to week 50.11 ± 0.54 (46)−0.26 ± 0.80 (46)−5.6 ± 18.0 (46)0.5 ± 7.5 (46)−10.7 ± 27.2 (46)
0.17 (0.64)0 (1)−3.9 (13.0)0 (0)−4.2 (20.0)
0.1930.056b0.002b0.124b<0.001b

Change from baseline to week 60.17 ± 0.58 (46)0.02 ± 0.86 (46)−4.8 ± 14.1 (46)−1.2 ± 5.8 (46)−11.6 ± 20.6 (46)
0.24 (0.65)0 (0)−4 (12.8)0 (0)−4.5 (21.1)
0.0510.891b<0.001b0.167b<0.001b

Change from baseline to week 70.18 ± 0.53 (46)−0.15 ± 0.73 (46)−5.0 ± 16.9 (46)−2.0 ± 7.4 (46)−11.6 ± 24.2 (46)
0.22 (0.67)0 (1)0 (14.1)0 (0)−6.7 (21.1)
0.0280.284b0.002b0.046b<0.001b

Change from baseline to week 80.18 ± 0.64 (46)−0.07 ± 0.95 (46)−5.6 ± 19.1 (46)−2.2 ± 8.3 (46)−27 ± 108 (46)
0.28 (0.81)0 (1.75)−1.7 (14.0)0 (2.9)−6 (21.7)
0.0630.432b<0.001b0.019b<0.001b

n: number; SD: standard deviation. aWithin-group comparisons were made using the paired Student’s t-test. bLogarithmic transformation required to achieve normality. Probability values ≤0.05 are statistically significant.