Phenolic-Rich Baccaurea angulata Modulates Inflammatory Biomarkers of Atherosclerosis

Table 2

Effects of B. angulata WF juice doses on serum ICAM-1, VCAM-1, CRP, TNF-α, and P-selectin.

Groups	ICAM-1 (ng/ml)	VCAM-1 (pg/ml)	CRP (pg/ml)	TNF-α (pg/ml)	P-selectin (pg/ml)
CH	21.49 ± 4.07^a	352.83 ± 16.98^a	47.48 ± 5.16^a	123.71 ± 13.06^a	30.36 ± 2.40^a
C1	7.88 ± 0.96^b	308.49 ± 11.79^a,b	44.42 ± 6.99^a	37.16 ± 4.11^b	15.05 ± 1.73^b
C2	4.56 ± 0.68^c	337.67 ± 11.95^a,b	36.78 ± 4.78^a	27.76 ± 3.89^b	15.50 ± 3.21^b
C3	2.78 ± 0.16^c,d	173.82 ± 9.83^b	5.75 ± 1.56^b	13.64 ± 2.19^b	12.43 ± 2.45^b
N	1.08 ± 0.26^d	278 ± 12.22^a,b	14.45 ± 3.64^b	6.45 ± 0.47^c	14.30 ± 1.05^b
N1	0.93 ± 0.20^d	265.76 ± 10.54^a,b	5.96 ± 1.38^b	7.38 ± 1.46^c	8.90 ± 0.73^c
N2	0.95 ± 0.18^d	198.71 ± 9.49^b	6.38 ± 0.73^b	6.68 ± 0.23^c	7.57 ± 0.75^c

Values are given as mean ± SD (). ^a,b,c,dValues not sharing a common superscript letter within the same column differ significantly at . CH: 1% cholesterol diet; C1: 1% cholesterol diet and 0.5 ml/kg/day B. angulata WF juice; C2: 1%. cholesterol diet and 1.0 ml/kg/day B. angulata WF juice; C3: 1% cholesterol diet and 1.5 ml/kg/day B. angulata WF juice; N: standard pellet; N1: standard pellet and 0.5 ml/kg/day B. angulata WF juice; N2: standard pellet and 1.0 ml/kg/day B. angulata WF juice; ICAM-1: intercellular cell adhesion molecule-1; VCAM-1: vascular cell adhesion molecule-1; CRP: C-reactive protein; TNF-α: tumor necrosis factor-α.