Research Article

The Hepatoprotective Effect of Jaboticaba Peel Powder in a Rat Model of Type 2 Diabetes Mellitus Involves the Modulation of Thiol/Disulfide Redox State through the Upregulation of Glutathione Synthesis

Table 1

Treatment of experimental groups.

GroupsDietInjection (i.p.)Drinking solution

Control (nondiabetic)Commercial chow dietVehicleVehicle#
Diabetic-vehicleHFDSTZVehicle#
Diabetic JPP-IHFDSTZ2.7 g JPP/L of vehicle
Diabetic JPP-IIHFDSTZ5.4 g JPP/L of vehicle
Diabetic JPP-IIIHFDSTZ10.8 g JPP/L of vehicle

STZ vehicle was 0.1 M citrate buffer, pH 4.4. #Water containing 0.5% carboxymethyl cellulose was used as vehicle to stabilize the drinking suspension of JPP. STZ: streptozotocin; HFD: high-fat diet.