Research Article

Long-Term Ketogenic Diet Induces Metabolic Acidosis, Anemia, and Oxidative Stress in Healthy Wistar Rats

Table 5

The comparison of blood gas profiles of rats receiving standard and ketogenic diets for 60 days.

Blood gasNDietMean ± SEM value

pH8Standard7.52 ± 0.010.001
7Ketogenic7.36 ± 0.02

pCO2 (mmHg)8Standard27.63 ± 1.341.00
7Ketogenic35.72 ± 5.96

pO2 (mmHg)8Standard107.75 ± 2.930.32
7Ketogenic88.14 ± 12.14

HCO3- (mmol/l)8Standard22.75 ± 0.790.48
7Ketogenic19.74 ± 2.54

Base excess (mmol/l)8Standard1.08 ± 0.430.04
7Ketogenic0.32 ± 0.11

TCO2 (mmol/l)8Standard23.63 ± 0.840.56
7Ketogenic20.86 ± 2.77

SO2 (%)8Standard98.63 ± 0.180.20
7Ketogenic90.29 ± 6.18