Research Article

Novel Organic Mineral Complex Prevents High-Fat Diet-Induced Changes in the Gut and Liver of Male Sprague-Dawley Rats

Figure 5

Differently abundant taxa after 10 weeks of either Chow or HFD. (a) Linear discriminate analysis of effect size (LEfSe) results depicting different microbial taxonomic signatures in fecal samples collected from male Sprague-Dawley rats fed an HFD (n = 5-6/group) at week 10 in comparison to Chow-fed samples at week 10. Fecal samples collected from HFD-fed rats were more abundant in the following phyla: Bacteroidetes, Firmicutes, Clostridium, Deferribacteres, Proteobacteria, and Tenericutes (LDA > 2.0 : 18). No other differences were detected. (b) Cladogram depicting differentially abundant microbial taxa in stool samples collected from male Sprague-Dawley rats fed a high-fat diet (n = 5-6) for 10 weeks. Microbial taxa enriched in HFD rats are shown in red.